Metabolic Diseases | CardioMet Trial Database

Study

AllACCESS (Phase 2b)ACHIEVE-1ACHIEVE-3ALPINE 2/3ALPINE-4Ambery et alAMPLITUDE-MAMPLITUDE-OAMPLITUDE-O ExploratoryAMYCRETINARCONARGON-1Aroda VR et alAROINHBE-1001ATLASATTAIN-1ATTAIN-2BALANCEBALANCED Phase 2aBELIEVEBillings KL et alBlüher et alBrowne et alCENTAURCoskun et alCT388-103 trialDREAMS-1DREAMS-2DREAMS-3 Phase 3DUET Phase 2aEcnoglutide (XW003)EECOH-1EECOH-2Efimosfermin alfa (BOS-580) trialEMMINENCE Phase 2bENLIVEN Phase 2bENTRIGUE-MIRNAESSENCEFASCINATE Phase 2bFLIGHT-FXRFlint A et alFLOWFLOW SGLT2Frias et alFrias JP et alGLORY-1GLORY-2 Phase 3Gómez-Romero M et alHARMONYHarrison S et alHarrison SA et alHeise T et alHesse D et alIMPACT Phase 2bIMPACT-Phase 2b MASHION224-CS2IONIS-DGAT2Jastreboff et alJi L et alLacobellis G et alLau et alLe Roux CW et alLi W et alLoomba R et alMAESTRO-NASHMariTide Phase 2 ObesityMather KJ et alMazdutide (IB1362)MOMENTUMNahra R et alNATIVENewsome P.N et alNN9931-4296NN9931-4492 InvestigatorsOASIS 1OASIS 2OASIS 4Parker V.E.R et alPatel K et alPIONEER 1PIONEER 10PIONEER 11PIONEER 12PIONEER 2PIONEER 3PIONEER 4PIONEER 5PIONEER 6PIONEER 7PIONEER 8PIONEER 9PIONEER PLUSPROXYMOREDEFINE 1REDEFINE 2REDEFINE-2REDEFINE-4REGENERATEREIMAGINE-2Rosenstock et alSanyal A et alSanyal et alSELECTSELECT CKDSELECT MWSELECT SubstudySelvarajah et alShah VN et alSiddiqui MS et alSMARTSOULSTEP 1STEP 1 ExtendedSTEP 10STEP 11STEP 2STEP 3STEP 4STEP 5STEP 6STEP 7STEP 8STEP 9STEP HFpEFSTEP HFpEF DMSTEP TEENSSTEP UPSTEP UP (NN9536-4999)STEP UP MRISTEP UP T2DSTRIDESUMMIT-1SUMMIT-CMR SubstudySURMOUNT-1SURMOUNT-1 (Study 2)SURMOUNT-2SURMOUNT-3SURMOUNT-4SURMOUNT-5SURMOUNT-CNSURMOUNT-MMOSURMOUNT-OSASURMOUNT-OSA (Trial 1)SURMOUNT-OSA (Trial 2)SURPASS J-monoSURPASS-1SURPASS-2SURPASS-3SURPASS-3 MRISURPASS-4SURPASS-5SURPASS-6SURPASS-CN-INSSURPASS-CVOTSURPASS-PEDSSUSTAIN 1SUSTAIN 10SUSTAIN 11SUSTAIN 2SUSTAIN 3SUSTAIN 4SUSTAIN 5SUSTAIN 6SUSTAIN 7SUSTAIN 8SUSTAIN 9SUSTAIN FORTESYMMETRYSYNERGY-NASHTRANSCEND-T2D-1TRIUMPH OUTCOMESTRIUMPH-4VENTURE OralVENTURE SubcutaneousVESPER-1VOYAGEWharton et alWu H et alZhang B et alZhao L et alZhou J et alZhu D et al

Drug

Outcome

Weight change (%)

Phase

Diabetes Status

Administration

Show placebo effect

Obesity and diabetes agents

Pool estimates